Viagra creating something special

Viagra 
The drug restores the normal response to sexual stimulation. Properly, the physiological mechanism that provides an erection is not possible without the isolation of nitric oxide in the cavernous body during sexual stimulation. It activates a special enzyme called guanylate cyclase, which results in increased levels of cGMP (cyclic guanosine monophosphate), relaxing the muscles of the corpora cavernosa and increasing blood flow to the genitals. Sildenafiles, an active ingredient in VIAGRA, is a selective inhibitor of PDE5 (phosphodiesterasade type 5), which has a breakdown of cGMP in the corpora cavernosa. The drug is characterized by the peripheral action in the erection of the penis. It is noteworthy that sildenafil relaxes the corpora cavernosa not directly, but uses the function of relaxing nitrogen oxide.

Before considering Generic Viagra for sale, it is very required to follow some issues for seller mentioning below

The drug was well tolerated in healthy people, after a single application in an amount not exceeding 100 mg did not cause clinically significant alterations.

Indications for use:
The drug is prescribed for a variety of erectile dysfunction (usually psychogenic, organic or mixed).

How to use:
The tablets of the drug are taken orally, one hour before the planned sexual intercourse. The optimal single dose for adults is 50 mg once daily. Taking into account tolerance and individual efficacy, the dose can be reduced to 25 mg or increased to 100 mg. 100 mg per day - this is the maximum single dose.

For older people they don't have to change the standard dose.

The secondary effects:

The drug is well tolerated. In some cases, side effects of:

Ø  Central nervous system (insomnia, dizziness and increased muscle tone)
Ø  Cardiovascular system (redness, headache, vasodilation)
Ø  Skeletal muscle system (joint and muscle pain)
Ø  of the gastrointestinal tract (nausea, diarrhea, dyspepsia)
Ø  of the skin (rash)
Ø  sense organs (conjunctivitis, blurred vision, increased color perception, change in color perception)
Ø  Respiratory system (disorders, pharyngitis, sinusitis, rhinitis, nasal congestion, respiratory tract infection to breathe)
Ø  Urogenital system (work prostate disorder, urinary tract infections

Among other side effects, flu symptoms, back or stomach pain were observed. Rare cases of priapism have been observed.

Contraindications:
The drug is contraindicated in people with hypersensitivity to the drug and with anatomical deformations of the penis (Peyronie's disease, cavernous fibrosis, angulation).

Also, do not use this medication in the following violations:

v  Increased bleeding tendency
v  Exacerbation of peptic ulcer disease of the gastrointestinal tract
v  Liver violations, kidney failure or cirrhosis especially severe
v  Diseases that develop priapism, including leukemia, multiple myeloma and sickle cell anemia
v  Severe hypotension or high blood pressure

Various heart diseases, including unstable angina pectoris, dangerous arrhythmia form and heart failure.

If the patient has had a stroke or myocardial infarction, in the next six months, the medication should not be used. In addition, Viagra is not indicated for children. Simultaneous use of the drug with nitrates and nitric oxide donors is strictly prohibited. Men who are contraindicated sexual activity should not use Viagra.

The pregnancy:
This drug is not indicated for women. They have conducted reproductive experiments in rabbits and rats, and the results have not revealed teratogenic effects of Viagra. The fetus develops without deviations and violations. They have also investigated the morphology of sperm and the activity of volunteers in a single dose. No irregularities were found.

Interaction with other medications:
The reception of erythromycin, cimetidine and ketoconazole is characterized by a decrease in clearance and subsequent increase in the content of Sildenafil in the patient's blood plasma. Viagra together with sodium nitroprusside increases its antiplatelet effect. In addition, when combined with nitrate medication increases the antihypertensive effect. It can even lead to death. It is also dangerous for the life of the drug simultaneously with oral hypoglycemic drugs, BCCI, and beta-blockers.

Overdose:
Studies have shown that with VIAGRA overdose in patients the side effects have clearly appeared. In this case, as a treatment, you should use symptomatic therapy. Dialysis is not effective because the active substance is activated and quickly binds to plasma proteins.

The way of production:
Viagra is distributed as film-coated tablets. The tablets are in an aluminum foil blister, which in turn is in a cardboard box.

Storage conditions:
Viagra is stored in a dry place, out of reach of children. The storage temperature should not exceed 30 ° C. The shelf life is 2 years. Do not use expired medications.

Synonyms:
Sildenafil

The ingredients:
The main active ingredient essildenafil, presented in a citrate form. As auxiliary substances are used: anhydrous calcium hydrogen phosphate, magnesium stearate, croscarmellose sodium and titanium dioxide (E 171), triacetin, MCC, hypromellose, indigo aluminum lacquer carmine (E 132), lactose.

Further:
The drug is released in pharmacies with a prescription. Nowadays Generic viagra for selling  approval need to required

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